Why Do Drug Names End in IB?

Why do drug names end in IB?
The ending letters (stem) of the generic names are like surnames that tell what family the drug is from and how the drug works to kill cancer cells. Monoclonal antibodies end with the stem “”-mab”” and small molecule inhibitors end with the stem “”-ib””.
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You may have noticed that many drug names end in the letters “IB” if you’ve ever taken medication. What does this entail, then? A drug’s generic name is often prefixed with “-ib” to signify that it is a member of the nonsteroidal anti-inflammatory drug (NSAID) class of pharmaceuticals.

NSAIDs are a class of medications that are frequently prescribed and are primarily used to treat fever, inflammation, and discomfort. They function by preventing the body from producing specific molecules that cause pain and inflammation. Ibuprofen, naproxen, and ketoprofen are typical examples of NSAIDs that finish in “-ib”.

However, not all medications with the “-ine” ending are NSAIDs. In fact, this suffix is frequently seen in the names of medications from a variety of classifications, such as antibiotics, antihistamines, and antiarrhythmics. Penicilline, cetirizine, and amiodarone are a few examples of medications with a “-ine” ending that do not fall under the NSAID category.

There are a few various ways that pharmaceuticals can be categorized when it comes to classifications. The five drug classifications is one widely used system that classifies drugs into five groups according to how they work: 2. CNS stimulants, such amphetamines and caffeine. 1. Central nervous system (CNS) depressants, like benzodiazepines and barbiturates. 3. Drugs that are addictive, such morphine and fentanyl 4. Hallucinogens like LSD and psilocybin 5. Steroids like cortisol and testosterone The U.S. Drug Enforcement Administration (DEA) uses the six classes of drugs classification system to group banned substances according to their propensity for abuse and dependency. The six classes are as follows: 1. Schedule I: Substances with a high potential for misuse and no currently recognized medicinal value, such as heroin and LSD 2. Schedule II: Drugs like oxycodone and fentanyl that have a high potential for misuse and dependence 3. Schedule III includes drugs like codeine and anabolic steroids that have a moderate to low misuse and dependency potential. 4. Schedule IV: Drugs with low abuse and dependence potential, such alprazolam and diazepam 5. Schedule V: Substances with a limited abuse and dependency potential, such as codeine-containing cough syrup 6. Unscheduled: Substances like coffee and nicotine that do not fit into any of the aforementioned categories Drug names that don’t end in “-ib” include acetaminophen (a painkiller and fever reducer), lisinopril (a blood pressure medication), and metformin (a prescription used to treat diabetes).

Despite the fact that many NSAIDs do have a “-ib” ending, not all medications with a “-ine” ending fall into this category. Drugs can be categorized in a number of ways, including the six drug classes the DEA uses and the five drug classifications. No matter how they are labeled or what their suffix is, it’s crucial to take pharmaceuticals exactly as prescribed by a doctor and to be aware of any possible adverse effects or drug interactions.